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siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse
RNA interference (RNAi) serves as a powerful and widely used gene silencing tool for basic biological research and is being developed as a therapeutic avenue to suppress disease-causing genes. However, the specificity and safety of RNAi strategies remains under scrutiny because small inhibitory RNAs...
Autores principales: | Boudreau, Ryan L., Spengler, Ryan M., Hylock, Ray H., Kusenda, Brandyn J., Davis, Heather A., Eichmann, David A., Davidson, Beverly L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592398/ https://www.ncbi.nlm.nih.gov/pubmed/22941647 http://dx.doi.org/10.1093/nar/gks797 |
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