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Mechanism of promoter repression by Lac repressor–DNA loops

The Escherichia coli lactose (lac) operon encodes the first genetic switch to be discovered, and lac remains a paradigm for studying negative and positive control of gene expression. Negative control is believed to involve competition of RNA polymerase and Lac repressor for overlapping binding sites...

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Detalles Bibliográficos
Autores principales: Becker, Nicole A., Peters, Justin P., Lionberger, Troy A., Maher, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592455/
https://www.ncbi.nlm.nih.gov/pubmed/23143103
http://dx.doi.org/10.1093/nar/gks1011