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Mechanism of promoter repression by Lac repressor–DNA loops
The Escherichia coli lactose (lac) operon encodes the first genetic switch to be discovered, and lac remains a paradigm for studying negative and positive control of gene expression. Negative control is believed to involve competition of RNA polymerase and Lac repressor for overlapping binding sites...
Autores principales: | Becker, Nicole A., Peters, Justin P., Lionberger, Troy A., Maher, L. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592455/ https://www.ncbi.nlm.nih.gov/pubmed/23143103 http://dx.doi.org/10.1093/nar/gks1011 |
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