Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA

Type IIB restriction-modification systems, such as BcgI, feature a single protein with both endonuclease and methyltransferase activities. Type IIB nucleases require two recognition sites and cut both strands on both sides of their unmodified sites. BcgI cuts all eight target phosphodiester bonds be...

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Detalles Bibliográficos
Autores principales: Smith, Rachel M., Marshall, Jacqueline J. T., Jacklin, Alistair J., Retter, Susan E., Halford, Stephen E., Sobott, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592470/
https://www.ncbi.nlm.nih.gov/pubmed/23147005
http://dx.doi.org/10.1093/nar/gks1023

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