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Rationally designed bidirectional promoter improves the evolutionary stability of synthetic genetic circuits
One problem with synthetic genes in genetically engineered organisms is that these foreign DNAs will eventually lose their functions over evolutionary time in absence of selective pressures. This general limitation can restrain the long-term study and industrial application of synthetic genetic circ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592475/ https://www.ncbi.nlm.nih.gov/pubmed/23093602 http://dx.doi.org/10.1093/nar/gks972 |