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Genetic interactions suggest multiple distinct roles of the arch and core helicase domains of Mtr4 in Rrp6 and exosome function

The RNA exosome is responsible for a wide variety of RNA processing and degradation reactions. The activity and specificity of the RNA exosome is thought to be controlled by a number of cofactors. Mtr4 is an essential RNA-dependent adenosine triphosphatase that is required for all of the nuclear fun...

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Detalles Bibliográficos
Autores principales: Klauer, A. Alejandra, van Hoof, Ambro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592479/
https://www.ncbi.nlm.nih.gov/pubmed/23143101
http://dx.doi.org/10.1093/nar/gks1013