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Protein Kinase C Delta Negatively Modulates Canonical Wnt Pathway and Cell Proliferation in Colon Tumor Cell Lines

The tumor suppressor Adenomatous Polyposis coli (APC) gene is mutated or lost in most colon cancers. Alterations in Protein kinase C (PKC) isozyme expression and aberrant regulation also comprise early events in intestinal carcinomas. Here we show that PKCδ expression levels are decreased in colon t...

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Detalles Bibliográficos
Autores principales: Hernández-Maqueda, José G., Luna-Ulloa, Luis Bernardo, Santoyo-Ramos, Paula, Castañeda-Patlán, M. Cristina, Robles-Flores, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592802/
https://www.ncbi.nlm.nih.gov/pubmed/23520519
http://dx.doi.org/10.1371/journal.pone.0058540