2,3,7,8-Tetrachlorodibenzo-p-Dioxin Promotes BHV-1 Infection in Mammalian Cells by Interfering with Iron Homeostasis Regulation

Mammalian cells require iron to satisfy metabolic needs or to accomplish specialized functions, and DNA viruses, like bovine herpesvirus 1 (BHV-1), require an iron-replete host to efficiently replicate, so that iron bioavailability is an important component of viral virulence. Cellular iron metaboli...

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Detalles Bibliográficos
Autores principales: Fiorito, Filomena, Irace, Carlo, Di Pascale, Antonio, Colonna, Alfredo, Iovane, Giuseppe, Pagnini, Ugo, Santamaria, Rita, De Martino, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592816/
https://www.ncbi.nlm.nih.gov/pubmed/23520538
http://dx.doi.org/10.1371/journal.pone.0058845

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