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Global Identification of Genes Related to Nutrient Deficiency in Intervertebral Disc Cells in an Experimental Nutrient Deprivation Model
BACKGROUND: Intervertebral disc degeneration is a significant cause of degenerative spinal diseases. Nucleus pulposus (NP) cells reportedly fail to survive in large degenerated discs with limited nutrient availability. Therefore, understanding the regulatory mechanism of the molecular response of NP...
Autores principales: | Sudo, Hideki, Yamada, Katsuhisa, Iwasaki, Koji, Higashi, Hideaki, Ito, Manabu, Minami, Akio, Iwasaki, Norimasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592817/ https://www.ncbi.nlm.nih.gov/pubmed/23520533 http://dx.doi.org/10.1371/journal.pone.0058806 |
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