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Early Differentiated CD138(high)MHCII(+)IgG(+) Plasma Cells Express CXCR3 and Localize into Inflamed Kidneys of Lupus Mice
Humoral responses are central to the development of chronic autoimmune diseases such as systemic lupus erythematosus. Indeed, autoantibody deposition is responsible for tissue damage, the kidneys being one of the main target organs. As the source of pathogenic antibodies, plasma cells are therefore...
Autores principales: | Lacotte, Stéphanie, Decossas, Marion, Le Coz, Carole, Brun, Susana, Muller, Sylviane, Dumortier, Hélène |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592892/ https://www.ncbi.nlm.nih.gov/pubmed/23520491 http://dx.doi.org/10.1371/journal.pone.0058140 |
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