Cargando…

N-Cadherin Expression Is Associated with Acquisition of EMT Phenotype and with Enhanced Invasion in Erlotinib-Resistant Lung Cancer Cell Lines

BACKGROUND: The epidermal growth-factor receptor tyrosine kinase inhibitors have been effective in non-small cell lung cancer patients. However, acquired resistance eventually develops in most patients despite an initial positive response. Emerging evidence suggests that there is a molecular connect...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaoju, Liu, Guangzhi, Kang, Yi, Dong, Zhaogang, Qian, Qiyu, Ma, Xitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592915/
https://www.ncbi.nlm.nih.gov/pubmed/23520479
http://dx.doi.org/10.1371/journal.pone.0057692