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The impact of microcarrier culture optimization on the glycosylation profile of a monoclonal antibody
Microcarriers are widely used for the large-scale culture of attachment-dependent cells with increased cell densities and, ultimately, higher product yield. In these processes, the specific culture conditions can affect the quality of the product, which is closely related to its glycosylation patter...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing AG
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592997/ https://www.ncbi.nlm.nih.gov/pubmed/23487430 http://dx.doi.org/10.1186/2193-1801-2-25 |