Cargando…

The impact of microcarrier culture optimization on the glycosylation profile of a monoclonal antibody

Microcarriers are widely used for the large-scale culture of attachment-dependent cells with increased cell densities and, ultimately, higher product yield. In these processes, the specific culture conditions can affect the quality of the product, which is closely related to its glycosylation patter...

Descripción completa

Detalles Bibliográficos
Autores principales: Costa, Ana Rita, Withers, Joanne, Rodrigues, Maria Elisa, McLoughlin, Niaobh, Henriques, Mariana, Oliveira, Rosário, Rudd, Pauline M, Azeredo, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592997/
https://www.ncbi.nlm.nih.gov/pubmed/23487430
http://dx.doi.org/10.1186/2193-1801-2-25