Cargando…
The impact of microcarrier culture optimization on the glycosylation profile of a monoclonal antibody
Microcarriers are widely used for the large-scale culture of attachment-dependent cells with increased cell densities and, ultimately, higher product yield. In these processes, the specific culture conditions can affect the quality of the product, which is closely related to its glycosylation patter...
Autores principales: | Costa, Ana Rita, Withers, Joanne, Rodrigues, Maria Elisa, McLoughlin, Niaobh, Henriques, Mariana, Oliveira, Rosário, Rudd, Pauline M, Azeredo, Joana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing AG
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592997/ https://www.ncbi.nlm.nih.gov/pubmed/23487430 http://dx.doi.org/10.1186/2193-1801-2-25 |
Ejemplares similares
-
Preliminary evaluation of microcarrier culture for growth and monoclonal antibody production of CHO-K1 cells
por: Rodrigues, M Elisa, et al.
Publicado: (2011) -
Strategies for adaptation of mAb-producing CHO cells to serum-free medium
por: Costa, A Rita, et al.
Publicado: (2011) -
Microcarriers for Upscaling Cultured Meat Production
por: Bodiou, Vincent, et al.
Publicado: (2020) -
Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells
por: Burleigh, Susan C, et al.
Publicado: (2011) -
Shaped 3D microcarriers for adherent cell culture and analysis
por: Wu, Chueh-Yu, et al.
Publicado: (2018)