Deficiency in pulmonary surfactant proteins in mice with fatty acid binding protein 4-Cre-mediated knockout of the tuberous sclerosis complex 1 gene

NEW FINDINGS: What is the central question of this study? Does tuberous sclerosis complex 1–mammalian target of rapamycin (mTOR) signalling regulate the synthesis of surfactant proteins A and B and, if so, can this contribute to the postnatal death of Fabp4-Tsc1cKO mice? What is the main finding and...

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Detalles Bibliográficos
Autores principales: Xiang, Xinxin, Yuan, Fang, Zhao, Jing, Li, Ziru, Wang, Xian, Guan, Youfei, Tang, Chaoshu, Sun, Guang, Li, Yin, Zhang, Weizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593000/
https://www.ncbi.nlm.nih.gov/pubmed/23143994
http://dx.doi.org/10.1113/expphysiol.2012.069674

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