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β-Lapachone, a substrate of NAD(P)H:quinone oxidoreductase, induces anti-inflammatory heme oxygenase-1 via AMP-activated protein kinase activation in RAW264.7 macrophages

AMP-activated protein kinase (AMPK), a crucial regulator of energy metabolic homeostasis, is suggested to regulate inflammatory responses, but its precise mechanisms are not fully understood. It has been reported that pharmacological activation of AMPK induces heme oxygenase-1 (HO-1) expression. β-L...

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Detalles Bibliográficos
Autores principales:	Byun, Seung Jae, Son, Young, Hwan Cho, Baik, Chung, Hun-Taeg, Pae, Hyun-Ock
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	the Society for Free Radical Research Japan 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593126/ https://www.ncbi.nlm.nih.gov/pubmed/23525626 http://dx.doi.org/10.3164/jcbn.12-80

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