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Cerebral paragonimiasis mimicking tuberculoma: First case report in India

An 8-year-old male child of Tuensang District, Nagaland, India, attended Civil Hospital, Tuensang, complaining of cough, fever, headache, and inability to move right arm since one month. On clinical suspicion of tubercular meningitis, anti-tubercular therapy was initiated and the patient was referre...

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Autores principales: Singh, T Shantikumar, Khamo, V, Sugiyama, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593464/
https://www.ncbi.nlm.nih.gov/pubmed/23507623
http://dx.doi.org/10.4103/2229-5070.72106
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author Singh, T Shantikumar
Khamo, V
Sugiyama, H
author_facet Singh, T Shantikumar
Khamo, V
Sugiyama, H
author_sort Singh, T Shantikumar
collection PubMed
description An 8-year-old male child of Tuensang District, Nagaland, India, attended Civil Hospital, Tuensang, complaining of cough, fever, headache, and inability to move right arm since one month. On clinical suspicion of tubercular meningitis, anti-tubercular therapy was initiated and the patient was referred to the Naga Hospital Authority. A brain computed tomography scan revealed an isodense area with surrounding edema on the left parietal lobe, which was diagnosed as tuberculoma and the anti-tubercular therapy was continued. As there was no sign of clinical improvement on completion of the three-month-ATD regimen, the patient was investigated for paragonimiasis. Laboratory investigations revealed peripheral blood eosinophilia, raised ESR, Paragonimus egg-positive sputum, and positive Enzyme-linked immunosorbent assay (ELISA) and ID tests for paragonimiasis. The Bacillus Calmette-Guérin (BCG) test and Acid Fast Bacilli (AFB) sputum smears were negative. Chest roentgenogram showed no abnormal findings. A final diagnosis of pulmonary paragonimiasis associated with cerebral paragonimiasis was made. The patient responded to praziquantel therapy. Cerebral paragonimiasis is a serious extrapulmonary form of paragonimiasis, sometimes life-threatening, but curable with praziquantel. It should be included in the differential diagnosis of cerebral granulomatous and other space-occupying lesions.
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spelling pubmed-35934642013-03-18 Cerebral paragonimiasis mimicking tuberculoma: First case report in India Singh, T Shantikumar Khamo, V Sugiyama, H Trop Parasitol Case Report An 8-year-old male child of Tuensang District, Nagaland, India, attended Civil Hospital, Tuensang, complaining of cough, fever, headache, and inability to move right arm since one month. On clinical suspicion of tubercular meningitis, anti-tubercular therapy was initiated and the patient was referred to the Naga Hospital Authority. A brain computed tomography scan revealed an isodense area with surrounding edema on the left parietal lobe, which was diagnosed as tuberculoma and the anti-tubercular therapy was continued. As there was no sign of clinical improvement on completion of the three-month-ATD regimen, the patient was investigated for paragonimiasis. Laboratory investigations revealed peripheral blood eosinophilia, raised ESR, Paragonimus egg-positive sputum, and positive Enzyme-linked immunosorbent assay (ELISA) and ID tests for paragonimiasis. The Bacillus Calmette-Guérin (BCG) test and Acid Fast Bacilli (AFB) sputum smears were negative. Chest roentgenogram showed no abnormal findings. A final diagnosis of pulmonary paragonimiasis associated with cerebral paragonimiasis was made. The patient responded to praziquantel therapy. Cerebral paragonimiasis is a serious extrapulmonary form of paragonimiasis, sometimes life-threatening, but curable with praziquantel. It should be included in the differential diagnosis of cerebral granulomatous and other space-occupying lesions. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3593464/ /pubmed/23507623 http://dx.doi.org/10.4103/2229-5070.72106 Text en Copyright: © Tropical Parasitology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Singh, T Shantikumar
Khamo, V
Sugiyama, H
Cerebral paragonimiasis mimicking tuberculoma: First case report in India
title Cerebral paragonimiasis mimicking tuberculoma: First case report in India
title_full Cerebral paragonimiasis mimicking tuberculoma: First case report in India
title_fullStr Cerebral paragonimiasis mimicking tuberculoma: First case report in India
title_full_unstemmed Cerebral paragonimiasis mimicking tuberculoma: First case report in India
title_short Cerebral paragonimiasis mimicking tuberculoma: First case report in India
title_sort cerebral paragonimiasis mimicking tuberculoma: first case report in india
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593464/
https://www.ncbi.nlm.nih.gov/pubmed/23507623
http://dx.doi.org/10.4103/2229-5070.72106
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