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Afatinib: emerging next-generation tyrosine kinase inhibitor for NSCLC

The discovery of epidermal growth-factor receptor (EGFR)-activating mutations and the introduction of oral EGFR tyrosine kinase inhibitors (EGFR-TKIs) have expanded the treatment options for patients with non-small cell lung cancer. The first two reversible EGFR-TKIs, erlotinib and gefitinib, are ap...

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Detalles Bibliográficos
Autores principales:	Nelson, Valerie, Ziehr, Jacqueline, Agulnik, Mark, Johnson, Melissa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594037/ https://www.ncbi.nlm.nih.gov/pubmed/23493883 http://dx.doi.org/10.2147/OTT.S23165

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