Norisoboldine Suppresses Osteoclast Differentiation through Preventing the Accumulation of TRAF6-TAK1 Complexes and Activation of MAPKs/NF-κB/c-Fos/NFATc1 Pathways

Norisoboldine (NOR) is the main alkaloid constituent in the dry root of Lindera aggregata (Sims) Kosterm. (L. strychnifolia Vill.). As reported previously, orally administered NOR displayed a robust inhibition of joint bone destruction present in both mouse collagen-induced arthritis and rat adjuvan...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Zhi-feng, Tong, Bei, Xia, Yu-feng, Lu, Qian, Chou, Gui-xin, Wang, Zheng-tao, Dai, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594163/
https://www.ncbi.nlm.nih.gov/pubmed/23536866
http://dx.doi.org/10.1371/journal.pone.0059171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594163/
https://www.ncbi.nlm.nih.gov/pubmed/23536866
http://dx.doi.org/10.1371/journal.pone.0059171

Ejemplares similares