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Cu(2+) Affects Amyloid-β (1–42) Aggregation by Increasing Peptide-Peptide Binding Forces
The link between metals, Alzheimer's disease (AD) and its implicated protein, amyloid-β (Aβ), is complex and highly studied. AD is believed to occur as a result of the misfolding and aggregation of Aβ. The dyshomeostasis of metal ions and their propensity to interact with Aβ has also been impli...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594192/ https://www.ncbi.nlm.nih.gov/pubmed/23536847 http://dx.doi.org/10.1371/journal.pone.0059005 |