Molecules Altering the Intracellular Thiol Content Modulate NF-kB and STAT-1/IRF-1 Signalling Pathways and IL-12 p40 and IL-27 p28 Production in Murine Macrophages

BACKGROUND: The aim of this study was to investigate the molecular mechanisms involved in the production of Th1 cytokines, namely IL-12 and IL-27, when the intra-macrophage redox state was altered by different chemical entities such as GSH-C4, which is reduced glutathione carrying an aliphatic chain...

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Detalles Bibliográficos
Autores principales: Fraternale, Alessandra, Crinelli, Rita, Casabianca, Anna, Paoletti, Maria Filomena, Orlandi, Chiara, Carloni, Elisa, Smietana, Michaël, Palamara, Anna Teresa, Magnani, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594194/
https://www.ncbi.nlm.nih.gov/pubmed/23536773
http://dx.doi.org/10.1371/journal.pone.0057866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594194/
https://www.ncbi.nlm.nih.gov/pubmed/23536773
http://dx.doi.org/10.1371/journal.pone.0057866

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