MTHFR C677T Polymorphism and Risk of Congenital Heart Defects: Evidence from 29 Case-Control and TDT Studies

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme for folate metabolism in humans; it is encoded by the MTHFR gene. Several studies have assessed the association between MTHFR C677T polymorphism and the risk of congenital heart defects (CHDs), while the results were inco...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wang, Yujia, Gong, Fangqi, Zhu, Weihua, Fu, Songling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594197/
https://www.ncbi.nlm.nih.gov/pubmed/23536781
http://dx.doi.org/10.1371/journal.pone.0058041

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