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Rapamycin Reverses Status Epilepticus-Induced Memory Deficits and Dendritic Damage

Cognitive impairments are prominent sequelae of prolonged continuous seizures (status epilepticus; SE) in humans and animal models. While often associated with dendritic injury, the underlying mechanisms remain elusive. The mammalian target of rapamycin complex 1 (mTORC1) pathway is hyperactivated f...

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Detalles Bibliográficos
Autores principales:	Brewster, Amy L., Lugo, Joaquin N., Patil, Vinit V., Lee, Wai L., Qian, Yan, Vanegas, Fabiola, Anderson, Anne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594232/ https://www.ncbi.nlm.nih.gov/pubmed/23536771 http://dx.doi.org/10.1371/journal.pone.0057808

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