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Fluid-Phase Pinocytosis of Native Low Density Lipoprotein Promotes Murine M-CSF Differentiated Macrophage Foam Cell Formation

During atherosclerosis, low-density lipoprotein (LDL)-derived cholesterol accumulates in macrophages to form foam cells. Macrophage uptake of LDL promotes foam cell formation but the mechanism mediating this process is not clear. The present study investigates the mechanism of LDL uptake for macroph...

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Detalles Bibliográficos
Autores principales: Barthwal, Manoj K., Anzinger, Joshua J., Xu, Qing, Bohnacker, Thomas, Wymann, Matthias P., Kruth, Howard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594233/
https://www.ncbi.nlm.nih.gov/pubmed/23536783
http://dx.doi.org/10.1371/journal.pone.0058054