Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells

CELF1 RNA-binding protein, otherwise called CUGBP1, associates and coordinates the degradation of GU-rich element (GRE) containing mRNA’s encoding factors important for cell growth, migration and apoptosis. Although many substrates of CELF1 have been identified, the biological significance of CELF1-...

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Detalles Bibliográficos
Autores principales: Talwar, Sudha, Balasubramanian, Sundaravadivel, Sundaramurthy, Santhanalakshmi, House, Reniqua, Wilusz, Carol J., Kuppuswamy, Dhandapani, D'Silva, Nisha, Gillespie, Marion Boyd, Hill, Elizabeth Goodwin, Palanisamy, Viswanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594286/
https://www.ncbi.nlm.nih.gov/pubmed/23324604
http://dx.doi.org/10.4161/rna.23315

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