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The Circadian Binding of CLOCK Protein to the Promoter of C/ebpα Gene in Mouse Cells
C/EBPα plays important roles in metabolism as well as in the maintenance of energy homeostasis. Here we describe loss of the circadian oscillation of C/ebpα expression in liver of Clock mutant mice. Reporter assays indicate Clock and Bmal significantly induced C/ebpα gene expression whereas Cry supp...
Autores principales: | Kawasaki, Haruhisa, Doi, Ryosuke, Ito, Kumpei, Shimoda, Masami, Ishida, Norio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594305/ https://www.ncbi.nlm.nih.gov/pubmed/23505471 http://dx.doi.org/10.1371/journal.pone.0058221 |
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