Saturation Mutagenesis of Lysine 12 Leads to the Identification of Derivatives of Nisin A with Enhanced Antimicrobial Activity

It is becoming increasingly apparent that innovations from the “golden age” of antibiotics are becoming ineffective, resulting in a pressing need for novel therapeutics. The bacteriocin family of antimicrobial peptides has attracted much attention in recent years as a source of potential alternative...

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Detalles Bibliográficos
Autores principales: Molloy, Evelyn M., Field, Des, Connor, Paula M. O'., Cotter, Paul D., Hill, Colin, Ross, R. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594307/
https://www.ncbi.nlm.nih.gov/pubmed/23505531
http://dx.doi.org/10.1371/journal.pone.0058530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594307/
https://www.ncbi.nlm.nih.gov/pubmed/23505531
http://dx.doi.org/10.1371/journal.pone.0058530

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