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Mucosal Tolerance to a Combination of ApoB and HSP60 Peptides Controls Plaque Progression and Stabilizes Vulnerable Plaque in Apob(tm2Sgy)Ldlr(tm1Her)/J Mice
Oral tolerance to auto antigens reduces the development of atherosclerosis in mouse models. However, the effect of immune tolerance to multiple self antigenic peptides in plaque progression and stabilization is not known. We studied the protective effect of mucosal tolerance to peptides from apolipo...
Autores principales: | Mundkur, Lakshmi, Mukhopadhyay, Rupak, Samson, Sonia, Varma, Meenakshi, Kale, Dnyaneswar, Chen, Daxin, Shivaprasad, Sneha, Sivanandan, Hemapriya, Soman, Vinod, Lu, Xinjie, Kakkar, Vijay V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594317/ https://www.ncbi.nlm.nih.gov/pubmed/23505495 http://dx.doi.org/10.1371/journal.pone.0058364 |
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