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Identification and Functional Characterization of FMN2, a Regulator of the Cyclin-Dependent Kinase Inhibitor p21

The ARF tumor suppressor is a central component of the cellular defense against oncogene activation in mammals. p14ARF activates p53 by binding and inhibiting HDM2, resulting, inter alia, in increased transcription and expression of the cyclin-dependent kinase inhibitor p21 and consequent cell-cycle...

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Detalles Bibliográficos
Autores principales:	Yamada, Kayo, Ono, Motoharu, Perkins, Neil D., Rocha, Sonia, Lamond, Angus I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594747/ https://www.ncbi.nlm.nih.gov/pubmed/23375502 http://dx.doi.org/10.1016/j.molcel.2012.12.023

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