Cellular Signaling Pathway Alterations and Potential Targeted Therapies for Medullary Thyroid Carcinoma

Parafollicular C-cell-derived medullary thyroid cancer (MTC) comprises 3% to 4% of all thyroid cancers. While cytotoxic treatments have been shown to have limited efficacy, targeted molecular therapies that inhibit rearranged during transfection (RET) and other tyrosine kinase receptors that are mai...

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Detalles Bibliográficos
Autores principales: Giunti, Serena, Antonelli, Alessandro, Amorosi, Andrea, Santarpia, Libero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594951/
https://www.ncbi.nlm.nih.gov/pubmed/23509459
http://dx.doi.org/10.1155/2013/803171

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