Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror

We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phant...

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Detalles Bibliográficos
Autores principales: Yang, Hao, Xi, Lei, Samuelson, Sean, Xie, Huikai, Yang, Lily, Jiang, Huabei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2013
Materias:
Multimodal Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595086/
https://www.ncbi.nlm.nih.gov/pubmed/23504287
http://dx.doi.org/10.1364/BOE.4.000427
Descripción
Sumario:We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.

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