Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror

We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phant...

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Detalles Bibliográficos
Autores principales: Yang, Hao, Xi, Lei, Samuelson, Sean, Xie, Huikai, Yang, Lily, Jiang, Huabei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2013
Materias:
Multimodal Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595086/
https://www.ncbi.nlm.nih.gov/pubmed/23504287
http://dx.doi.org/10.1364/BOE.4.000427
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author Yang, Hao
Xi, Lei
Samuelson, Sean
Xie, Huikai
Yang, Lily
Jiang, Huabei
author_facet Yang, Hao
Xi, Lei
Samuelson, Sean
Xie, Huikai
Yang, Lily
Jiang, Huabei
author_sort Yang, Hao
collection PubMed
description We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.
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spelling pubmed-35950862013-03-15 Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror Yang, Hao Xi, Lei Samuelson, Sean Xie, Huikai Yang, Lily Jiang, Huabei Biomed Opt Express Multimodal Imaging We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents. Optical Society of America 2013-02-15 /pmc/articles/PMC3595086/ /pubmed/23504287 http://dx.doi.org/10.1364/BOE.4.000427 Text en ©2013 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Multimodal Imaging
Yang, Hao
Xi, Lei
Samuelson, Sean
Xie, Huikai
Yang, Lily
Jiang, Huabei
Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror
title Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror
title_full Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror
title_fullStr Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror
title_full_unstemmed Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror
title_short Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror
title_sort handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a mems scanning mirror
topic Multimodal Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595086/
https://www.ncbi.nlm.nih.gov/pubmed/23504287
http://dx.doi.org/10.1364/BOE.4.000427
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