State-of-the-Art Fusion-Finder Algorithms Sensitivity and Specificity

Background. Gene fusions arising from chromosomal translocations have been implicated in cancer. RNA-seq has the potential to discover such rearrangements generating functional proteins (chimera/fusion). Recently, many methods for chimeras detection have been published. However, specificity and sens...

Descripción completa

Detalles Bibliográficos
Autores principales: Carrara, Matteo, Beccuti, Marco, Lazzarato, Fulvio, Cavallo, Federica, Cordero, Francesca, Donatelli, Susanna, Calogero, Raffaele A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595110/
https://www.ncbi.nlm.nih.gov/pubmed/23555082
http://dx.doi.org/10.1155/2013/340620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595110/
https://www.ncbi.nlm.nih.gov/pubmed/23555082
http://dx.doi.org/10.1155/2013/340620

Ejemplares similares