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CovR and VicRK Regulate Cell Surface Biogenesis Genes Required for Biofilm Formation in Streptococcus mutans
The two-component system VicRK and the orphan regulator CovR of Streptococcus mutans co-regulate a group of virulence genes associated with the synthesis of and interaction with extracellular polysaccharides of the biofilm matrix. Knockout mutants of vicK and covR display abnormal cell division and...
Autores principales: | Stipp, Rafael N., Boisvert, Heike, Smith, Daniel J., Höfling, José F., Duncan, Margaret J., Mattos-Graner, Renata O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595261/ https://www.ncbi.nlm.nih.gov/pubmed/23554881 http://dx.doi.org/10.1371/journal.pone.0058271 |
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