Functional Profiling Discovers the Dieldrin Organochlorinated Pesticide Affects Leucine Availability in Yeast

Exposure to organochlorinated pesticides such as dieldrin has been linked to Parkinson’s and Alzheimer’s diseases, endocrine disruption, and cancer, but the cellular and molecular mechanisms of toxicity behind these effects remain largely unknown. Here we demonstrate, using a functional genomics app...

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Detalles Bibliográficos
Autores principales: Gaytán, Brandon D., Loguinov, Alex V., Lantz, Stephen R., Lerot, Jan-Michael, Denslow, Nancy D., Vulpe, Chris D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595527/
https://www.ncbi.nlm.nih.gov/pubmed/23358190
http://dx.doi.org/10.1093/toxsci/kft018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595527/
https://www.ncbi.nlm.nih.gov/pubmed/23358190
http://dx.doi.org/10.1093/toxsci/kft018

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