Cargando…
Functional Profiling Discovers the Dieldrin Organochlorinated Pesticide Affects Leucine Availability in Yeast
Exposure to organochlorinated pesticides such as dieldrin has been linked to Parkinson’s and Alzheimer’s diseases, endocrine disruption, and cancer, but the cellular and molecular mechanisms of toxicity behind these effects remain largely unknown. Here we demonstrate, using a functional genomics app...
Autores principales: | Gaytán, Brandon D., Loguinov, Alex V., Lantz, Stephen R., Lerot, Jan-Michael, Denslow, Nancy D., Vulpe, Chris D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595527/ https://www.ncbi.nlm.nih.gov/pubmed/23358190 http://dx.doi.org/10.1093/toxsci/kft018 |
Ejemplares similares
-
A Genome-Wide Screen Identifies Yeast Genes Required for Tolerance to Technical Toxaphene, an Organochlorinated Pesticide Mixture
por: Gaytán, Brandon D., et al.
Publicado: (2013) -
Functional genomics indicates yeast requires Golgi/ER transport, chromatin remodeling, and DNA repair for low dose DMSO tolerance
por: Gaytán, Brandon D., et al.
Publicado: (2013) -
Organochlorines and breast cancer: effect of exposure to dieldrin on risk and survival
por: Høyer, AP, et al.
Publicado: (2001) -
Functional Toxicogenomic Profiling Expands Insight into Modulators of Formaldehyde Toxicity in Yeast
por: North, Matthew, et al.
Publicado: (2016) -
Developmental exposure to the Parkinson’s disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice
por: Boyd, Sierra L, et al.
Publicado: (2023)