The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes

IL-6 is a pleiotropic cytokine involved in the regulation of the immune response, inflammation, and hematopoeisis. Its elevated levels are found in a range of autoimmune and chronic inflammatory diseases. IL-6 is also involved in regulation of the balance between two T cell subsets: Tregs and Th17,...

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Autores principales: Ryba-Stanisławowska, Monika, Skrzypkowska, Maria, Myśliwska, Jolanta, Myśliwiec, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595664/
https://www.ncbi.nlm.nih.gov/pubmed/23533301
http://dx.doi.org/10.1155/2013/205284
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author Ryba-Stanisławowska, Monika
Skrzypkowska, Maria
Myśliwska, Jolanta
Myśliwiec, Małgorzata
author_facet Ryba-Stanisławowska, Monika
Skrzypkowska, Maria
Myśliwska, Jolanta
Myśliwiec, Małgorzata
author_sort Ryba-Stanisławowska, Monika
collection PubMed
description IL-6 is a pleiotropic cytokine involved in the regulation of the immune response, inflammation, and hematopoeisis. Its elevated levels are found in a range of autoimmune and chronic inflammatory diseases. IL-6 is also involved in regulation of the balance between two T cell subsets: Tregs and Th17, which have contradictory functions in the control of inflammation. The present study provides a quantitative analysis regarding the Th17/Treg cell balance in peripheral blood of children with type 1 diabetes and its association with serum IL-6 level.
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spelling pubmed-35956642013-03-26 The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes Ryba-Stanisławowska, Monika Skrzypkowska, Maria Myśliwska, Jolanta Myśliwiec, Małgorzata Mediators Inflamm Research Article IL-6 is a pleiotropic cytokine involved in the regulation of the immune response, inflammation, and hematopoeisis. Its elevated levels are found in a range of autoimmune and chronic inflammatory diseases. IL-6 is also involved in regulation of the balance between two T cell subsets: Tregs and Th17, which have contradictory functions in the control of inflammation. The present study provides a quantitative analysis regarding the Th17/Treg cell balance in peripheral blood of children with type 1 diabetes and its association with serum IL-6 level. Hindawi Publishing Corporation 2013 2013-02-21 /pmc/articles/PMC3595664/ /pubmed/23533301 http://dx.doi.org/10.1155/2013/205284 Text en Copyright © 2013 Monika Ryba-Stanisławowska et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ryba-Stanisławowska, Monika
Skrzypkowska, Maria
Myśliwska, Jolanta
Myśliwiec, Małgorzata
The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes
title The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes
title_full The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes
title_fullStr The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes
title_full_unstemmed The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes
title_short The Serum IL-6 Profile and Treg/Th17 Peripheral Cell Populations in Patients with Type 1 Diabetes
title_sort serum il-6 profile and treg/th17 peripheral cell populations in patients with type 1 diabetes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595664/
https://www.ncbi.nlm.nih.gov/pubmed/23533301
http://dx.doi.org/10.1155/2013/205284
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