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Microwave-assisted three-component domino reaction: Synthesis of indolodiazepinotriazoles

A microwave-assisted three-component protocol involving N-1 alkylation of 2-alkynylindoles with epichlorohydrin, ring opening of the epoxide with sodium azide, and an intramolecular Huisgen azide–internal alkyne 1,3-dipolar cycloaddition domino sequence has been described. The efficacy of the method...

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Detalles Bibliográficos
Autores principales:	Arigela, Rajesh K, Sharma, Sudhir K, Kumar, Brijesh, Kundu, Bijoy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2013
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596043/ https://www.ncbi.nlm.nih.gov/pubmed/23504610 http://dx.doi.org/10.3762/bjoc.9.41

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