GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer

The objective of this study was to determine copy number variant (CNV) and promoter genetic variants in glutathione S-transferase Mu class 1 (GSTM1) and the risk of recurrence (REC)/second primary tumor (SPT) in patients with previously diagnosed early stage head and neck cancer. Among 441 subjects,...

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Detalles Bibliográficos
Autores principales: Zhang, Xuemei, Huang, Maosheng, Wu, Xifeng, Kadlubar, Susan, Lin, Jie, Yu, Xinfeng, Fan, Chunyang, Ning, Baitang, Kadlubar, Fred F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596140/
https://www.ncbi.nlm.nih.gov/pubmed/23526580
http://dx.doi.org/10.2147/PGPM.S35949

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