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Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions
We examine how collagen substrate topography, free intracellular calcium ion concentration ([Ca(2+)](i), and the association of gelsolin with nonmuscle myosin IIA (NMMIIA) at collagen adhesions are regulated to enable collagen phagocytosis. Fibroblasts plated on planar, collagen-coated substrates sh...
Autores principales: | Arora, P. D., Wang, Y., Bresnick, A., Dawson, J., Janmey, P. A., McCulloch, C. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596245/ https://www.ncbi.nlm.nih.gov/pubmed/23325791 http://dx.doi.org/10.1091/mbc.E12-10-0754 |
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