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The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation

Cholera toxin (CT) traffics from the host cell surface to the endoplasmic reticulum (ER), where the toxin's catalytic CTA1 subunit retrotranslocates to the cytosol to induce toxicity. In the ER, CT is captured by the E3 ubiquitin ligase Hrd1 via an undefined mechanism to prepare for retrotransl...

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Detalles Bibliográficos
Autores principales:	Williams, Jeffrey M., Inoue, Takamasa, Banks, Lindsey, Tsai, Billy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596249/ https://www.ncbi.nlm.nih.gov/pubmed/23363602 http://dx.doi.org/10.1091/mbc.E12-07-0522

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