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GLIPR-2 Overexpression in HK-2 Cells Promotes Cell EMT and Migration through ERK1/2 Activation

The epithelial-to-mesenchymal transition (EMT) of tubular epithelial cells in the adult kidney is one of the key events in renal interstitial fibrosis. Glioma pathogenesis related-2 (GLIPR-2) has been shown to be up-regulated in proximal tubular cells (PTCs) in the fibrotic kidney. However, the biol...

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Detalles Bibliográficos
Autores principales: Huang, Shaoguang, Liu, Fei, Niu, Qin, Li, Yi, Liu, Chang, Zhang, Lele, Ni, Danni, Pu, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596275/
https://www.ncbi.nlm.nih.gov/pubmed/23516513
http://dx.doi.org/10.1371/journal.pone.0058574