Cargando…

The p90 Ribosomal S6 Kinase (RSK) Is a Mediator of Smooth Muscle Contractility

In the canonical model of smooth muscle (SM) contraction, the contractile force is generated by phosphorylation of the myosin regulatory light chain (RLC(20)) by the myosin light chain kinase (MLCK). Moreover, phosphorylation of the myosin targeting subunit (MYPT1) of the RLC(20) phosphatase (MLCP)...

Descripción completa

Detalles Bibliográficos
Autores principales: Artamonov, Mykhaylo, Momotani, Ko, Utepbergenov, Darkhan, Franke, Aaron, Khromov, Alexander, Derewenda, Zygmunt S., Somlyo, Avril V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596281/
https://www.ncbi.nlm.nih.gov/pubmed/23516539
http://dx.doi.org/10.1371/journal.pone.0058703