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Biogenesis and Proteolytic Processing of Lysosomal DNase II
Deoxyribonuclease II (DNase II) is a key enzyme in the phagocytic digestion of DNA from apoptotic nuclei. To understand the molecular properties of DNase II, particularly the processing, we prepared a polyclonal antibody against carboxyl-terminal sequences of mouse DNase II. In the present study, pa...
Autores principales: | Ohkouchi, Susumu, Shibata, Masahiro, Sasaki, Mitsuho, Koike, Masato, Safig, Paul, Peters, Christoph, Nagata, Shigekazu, Uchiyama, Yasuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596287/ https://www.ncbi.nlm.nih.gov/pubmed/23516607 http://dx.doi.org/10.1371/journal.pone.0059148 |
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