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Pathology Associated with AAV Mediated Expression of Beta Amyloid or C100 in Adult Mouse Hippocampus and Cerebellum

Accumulation of beta amyloid (Aβ) in the brain is a primary feature of Alzheimer’s disease (AD) but the exact molecular mechanisms by which Aβ exerts its toxic actions are not yet entirely clear. We documented pathological changes 3 and 6 months after localised injection of recombinant, bi-cistronic...

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Detalles Bibliográficos
Autores principales:	Drummond, Eleanor S., Muhling, Jill, Martins, Ralph N., Wijaya, Linda K., Ehlert, Erich M., Harvey, Alan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596293/ https://www.ncbi.nlm.nih.gov/pubmed/23516609 http://dx.doi.org/10.1371/journal.pone.0059166

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