Cargando…
Computer-Aided Design of Fragment Mixtures for NMR-Based Screening
Fragment-based drug discovery is widely applied both in industrial and in academic screening programs. Several screening techniques rely on NMR to detect binding of a fragment to a target. NMR-based methods are among the most sensitive techniques and have the further advantage of yielding a low rate...
Autores principales: | Arroyo, Xavier, Goldflam, Michael, Feliz, Miguel, Belda, Ignasi, Giralt, Ernest |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596306/ https://www.ncbi.nlm.nih.gov/pubmed/23516512 http://dx.doi.org/10.1371/journal.pone.0058571 |
Ejemplares similares
-
NMR quality control of fragment libraries for screening
por: Sreeramulu, Sridhar, et al.
Publicado: (2020) -
Computer- and NMR-Aided Design of Small-Molecule Inhibitors of the Hub1 Protein
por: Reyes Romero, Atilio, et al.
Publicado: (2022) -
Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor
por: Bayó‐Puxan, Núria, et al.
Publicado: (2015) -
NMR-Fragment Based Virtual Screening: A Brief Overview
por: Singh, Meenakshi, et al.
Publicado: (2018) -
Ultrafast Fragment
Screening Using Photo-Hyperpolarized
(CIDNP) NMR
por: Torres, Felix, et al.
Publicado: (2023)