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Low Density Lipoproteins Promote Unstable Calcium Handling Accompanied by Reduced SERCA2 and Connexin-40 Expression in Cardiomyocytes

The damaging effects of high plasma levels of cholesterol in the cardiovascular system are widely known, but little attention has been paid to direct effects on cardiomyocyte function. We therefore aimed at testing the hypothesis that Low Density Lipoprotein (LDL) cholesterol affects calcium dynamic...

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Detalles Bibliográficos
Autores principales: Barriga, Montserrat, Cal, Roi, Cabello, Nuria, Llach, Anna, Vallmitjana, Alexander, Benítez, Raúl, Badimon, Lina, Cinca, Juan, Llorente-Cortés, Vicenta, Hove-Madsen, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596315/
https://www.ncbi.nlm.nih.gov/pubmed/23516438
http://dx.doi.org/10.1371/journal.pone.0058128