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Differential Expression of the RANKL/RANK/OPG System Is Associated with Bone Metastasis in Human Non-Small Cell Lung Cancer

BACKGROUND: Human non-small cell lung cancer (NSCLC) patients exhibit a high propensity to develop skeletal metastasis, resulting in excessive osteolytic activity. The RANKL/RANK/OPG system, which plays a pivotal role in bone remodeling by regulating osteoclast formation and activity, is of potentia...

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Detalles Bibliográficos
Autores principales:	Peng, Xianbo, Guo, Wei, Ren, Tingting, Lou, Zhiyuan, Lu, Xinchang, Zhang, Shuai, Lu, Qunshan, Sun, Yifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596380/ https://www.ncbi.nlm.nih.gov/pubmed/23516466 http://dx.doi.org/10.1371/journal.pone.0058361

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