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Culturing on Wharton's Jelly Extract Delays Mesenchymal Stem Cell Senescence through p53 and p16INK4a/pRb Pathways

Mesenchymal stem cells (MSCs) hold great therapeutic potential. However, MSCs undergo replication senescence during the in vitro expansion process. Wharton's jelly from the human umbilical cord harbors a large number of MSCs. In this study, we hypothesized that Wharton's jelly would be ben...

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Detalles Bibliográficos
Autores principales:	Hao, Haojie, Chen, Guanghui, Liu, Jiejie, Ti, Dongdong, Zhao, Yali, Xu, Shenjun, Fu, Xiaobing, Han, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596399/ https://www.ncbi.nlm.nih.gov/pubmed/23516461 http://dx.doi.org/10.1371/journal.pone.0058314

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