Cargando…

Inhibition of TGF-β1 by eNOS gene transfer provides cardiac protection after myocardial infarction

OBJECTIVE: Endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) have been implicated in protection against myocardial ischemia injury. This study was designed to explore a new method of therapy for myocardial injury by eNOS gene transfection. METHODS: A rat model of myocardial infarction (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Wei, Chen, Xin, Liu, Peisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2010
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596549/ https://www.ncbi.nlm.nih.gov/pubmed/23554625 http://dx.doi.org/10.1016/S1674-8301(10)60023-1

Ejemplares similares

β3-Adrenoreceptor Stimulation Protects against Myocardial Infarction Injury via eNOS and nNOS Activation
por: Niu, Xiaolin, et al.
Publicado: (2014)

eNOS Gene Variants and the Risk of Premature Myocardial Infarction
por: Zigra, Aggeliki-Maria, et al.
Publicado: (2013)

Red blood cell eNOS is cardioprotective in acute myocardial infarction
por: Cortese-Krott, Miriam M., et al.
Publicado: (2022)

Association of the eNOS E298D polymorphism and the risk of myocardial infarction in the Greek population
por: Dafni, Chaido, et al.
Publicado: (2010)

Orientin Reduces Myocardial Infarction Size via eNOS/NO Signaling and Thus Mitigates Adverse Cardiac Remodeling
por: Li, Fangfang, et al.
Publicado: (2017)

Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling
por: Mu, Haiman, et al.
Publicado: (2019)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Phosphomimetic Modulation of eNOS Improves Myocardial Reperfusion and Mimics Cardiac Postconditioning in Mice
por: Pong, Terrence, et al.
Publicado: (2014)

Tanshinone IIA protects mice against atherosclerotic injury by activating the TGF-β/PI3K/Akt/eNOS pathway
por: Wang, Junyan, et al.
Publicado: (2020)

Heterozygous eNOS Deficient Mice as a Model to Examine the Effects of eNOS Haploinsufficiency on the Cerebral Circulation
por: Didion, Sean P.
Publicado: (2017)

mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling
por: Wang, Yiying, et al.
Publicado: (2022)

Atorvastatin at Reperfusion Reduces Myocardial Infarct Size in Mice by Activating eNOS in Bone Marrow-Derived Cells
por: Tian, Yikui, et al.
Publicado: (2014)

Association of genetic polymorphisms of eNOS with glaucoma
por: Liao, Qiong, et al.
Publicado: (2011)

SIRT1 protects against myocardial ischemia–reperfusion injury via activating eNOS in diabetic rats
por: Ding, Mingge, et al.
Publicado: (2015)

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014)

Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)

Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition
por: Chen, Zhenlong, et al.
Publicado: (2012)

Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine
por: Xie, Xinya, et al.
Publicado: (2018)

Data on eNOS T786 and G894T polymorphisms and peripheral blood eNOS mRNA levels in Sickle Cell Disease
por: Armenis, Iakovos, et al.
Publicado: (2016)

Seabuckthorn Pulp Oil Protects against Myocardial Ischemia–Reperfusion Injury in Rats through Activation of Akt/eNOS
por: Suchal, Kapil, et al.
Publicado: (2016)

Multiple inducers of endothelial NOS (eNOS) dysfunction in sickle cell disease
por: Hebbel, Robert P., et al.
Publicado: (2021)

Upregulation of iNOS and phosphorylated eNOS in the implantation‐induced blastocysts of mice
por: Seki, Misato, et al.
Publicado: (2023)

Expression of eNOS in kidneys from hypertensive patients
por: Gu, Xin, et al.
Publicado: (2010)

Frequency of eNOS polymorphisms in the Colombian general population
por: Serrano, Norma C, et al.
Publicado: (2010)

Neurogranin regulates eNOS function and endothelial activation
por: Cheriyan, Vino T., et al.
Publicado: (2020)

Paternal eNOS deficiency in mice affects glucose homeostasis and liver glycogen in male offspring without inheritance of eNOS deficiency itself
por: Hocher, Berthold, et al.
Publicado: (2022)

Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo
por: Bucci, Mariarosaria, et al.
Publicado: (2013)

Lack of association between the eNOS rs1800779 (A/G) polymorphism and the myocardial infarction incidence among the Iraqi Kurdish population
por: Khudhur, Zhikal O., et al.
Publicado: (2022)

Targeting feed-forward signaling of TGFβ/NOX4/DHFR/eNOS uncoupling/TGFβ axis with anti-TGFβ and folic acid attenuates formation of aortic aneurysms: Novel mechanisms and therapeutics
por: Huang, Kai, et al.
Publicado: (2020)

Corrigendum: Seabuckthorn Pulp Oil Protects against Myocardial Ischemia–Reperfusion Injury in Rats through Activation of Akt/eNOS
por: Suchal, Kapil, et al.
Publicado: (2019)

Recipient iNOS but Not eNOS Deficiency Reduces Luminal Narrowing in Tracheal Allografts
por: Minamoto, Kanji, et al.
Publicado: (2002)

Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS
por: Morsy, Mohamed A., et al.
Publicado: (2014)

Vanadyl sulfate inhibits NO production via threonine phosphorylation of eNOS.
por: Li, Zhuowei, et al.
Publicado: (2004)

Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment
por: Tan, Xing-Lin, et al.
Publicado: (2015)

eNOS Protects from Atherosclerosis Despite Relevant Superoxide Production by the Enzyme in apoE(−/−) Mice
por: Ponnuswamy, Padmapriya, et al.
Publicado: (2012)

Retraction: Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo
Publicado: (2019)

eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency
por: Gomaraschi, Monica, et al.
Publicado: (2014)

eNOS Gene Variant in Patients with Coronary Artery Disease
por: Abolhalaj, Milad, et al.
Publicado: (2013)

Berberine attenuates sepsis-induced cardiac dysfunction by upregulating the Akt/eNOS pathway in mice
por: Zhang, Hong, et al.
Publicado: (2022)

Brain-Derived Neurotrophic Factor Attenuates Septic Myocardial Dysfunction via eNOS/NO Pathway in Rats
por: Zeng, Ni, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s7jto2587lhovb3oj60td3fb80