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Identification of the metabolites of polybrominated diphenyl ether 99 and its related cytochrome P450s()

OBJECTIVE: To investigate the metabolites of polybrominated diphenyl ether 99 (BDE-99) and its related cytochrome P450s in an in vitro system. METHODS: Rat primary hepatocytes were isolated and treated with BDE-99 for 24-72 h. Metabolites were then extracted from the hepatocytes and media, and detec...

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Detalles Bibliográficos
Autores principales: Dong, Huibin, Li, Ziyin, Man, Xiaoming, Zhou, Jingping, Lu, Huiyuan, Wang, Shoulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596558/
https://www.ncbi.nlm.nih.gov/pubmed/23554634
http://dx.doi.org/10.1016/S1674-8301(10)60032-2